(BASF) -- BASF has developed a packaging system which sets new quality standards. In the future PeroXeal will protect the pharmaceutical excipient Kollidon, based on PVP (polyvinylpyrrolidone), even better against contact with oxygen and subsequent o xidation. This makes it possible to significantly reduce the peroxide level of Kollidon , making the excipient suitable for use in oxygen-sensitive formulations as well. Under the trade name Kollidon, PVP is used in tablets as a binder and as disintegrant.
"With PeroXeal BASF is setting new standards for excipients in terms of formula stability and purity and can thus help its customers in the pharmaceuticals industry achieve higher levels of patient safety," says Dr. Boris Jenniches, head of Global Business Management PVP at BASF. "With our new packaging concept we can significantly reduce peroxide values to a level comparable with that of naturally-based raw materials. This makes Kollidon a viable alternative to naturally-based raw materials". Generally, Kollidon as synthetic polymer shows less variability in processing compared to its natural counterparts. Further advantages of PeroXeal: The shelf life of the excipient is extended and by-products in the formulation are reduced.
MRC